Opposing roles of Ubp3-dependent deubiquitination regulate replicative life span and heat resistance
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چکیده
منابع مشابه
Opposing roles of Ubp3-dependent deubiquitination regulate replicative life span and heat resistance.
The interplay between molecular chaperones, ubiquitin/deubiquitinating enzymes, and proteasomes is a critical element in protein homeostasis. Among these factors, the conserved deubiquitinase, Ubp3, has the interesting ability, when overproduced, to suppress the requirement for the major cytosolic Hsp70 chaperones. Here, we show that Ubp3 overproduction counteracts deficiency of Hsp70s by the r...
متن کاملOpposing roles of Ubp3-dependent deubiqutination regulates replicative life span and heat resistance
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2014
ISSN: 0261-4189,1460-2075
DOI: 10.1002/embj.201386822